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Bone Marrow Transplant: Symptoms, Causes and Treatment

Bone Marrow Transplant Symptoms

  • 2021-06-22

A bone marrow transplant is a medical treatment that replaces your bone marrow with healthy cells from a donor. A bone marrow transplant is also known as a stem cell transplant. Find details about Bone Marrow Transplant Symptoms, Causes, and Treatment in India.

The procedure involves the replacement of the damaged bone marrow. Such core cells are often destroyed by infection, other ailments, or previously done chemotherapy. Doctors relocate blood stem cells traveling to the core cells region. There they produce new blood cells most of which belong to the nuclei body units.

Bone marrows comprise spongy, fatty tissues inside bones. These are responsible for the following sorts of activities:

  • RBCs carry oxygen and nutrients into our bodies.
  • WBC, the inept disease-combat blood cells.
  • Platelets; cause blood coagulation.


Your doctor would think of conducting a bone marrow transplant if h/she suspects that the tissues inside the bones are not performing properly. The probable reasons could be a chronic infection, some other conditions, and even a previous carcinoma treatment.

Predominant signs that drive doctors to such drastic decision include:

  • If the patient is diagnosed with aplastic anemia. The disease prohibits the marrows from producing new cells.
  • Damaged bone marrow.
  • Presence of conditions like leukemia, lymphoma, and multiple myeloma.
  • Congenital neutropenia; is an inherited condition causing repeated infections.
  • Sickle cell anemia; is also a hereditary condition that causes incidents to RBCs.
  • Thalassemia.


Treatment like a bone marrow transplant works in:

  • Substituting stem cells that were previously destroyed by chemotherapy.
  • It can heal up marrow issues by replacing them with healthy cells from a donor.
  • The procedure comprises adding donor cells that check the affected area and the adjacent regions to find and destroy cancerous cells.

You will be considered for such treatments for treating:

  • Both acute and chronic leukemia.
  • Lymphoma belonging to Hodgkin’s or non-Hodgkin’s types.
  • Myeloproliferative disorders
  • Amyloidosis
  • Myelofibrosis
  • Multiple myeloma
  • Aplastic anemia
  • Waldenstrom macroglobulinemia
  • Lupus, an autoimmune disease/
  • Sarcoma
  • Germ cell tumors.
  • Myelofibrosis.

It is a popular treatment process to heal the aftermaths of radiation therapy used in cancer treatment,

Treatment procedure

Your treatment starts after you are prepared for the procedure. Two types of approaches are followed in the bone marrow transplant procedure. These include:

  • The allogenic method where bone marrow cells are cropped from the donor one or two days ahead of the process. These may be your own cells also; they are stored in the clinic’s stem cell bank. They are retrieved from the place when your procedure system is ready.
  • In the bone marrow harvest procedure, the treatment cells collect the cells from both the hipbones by using a needle. It is a major surgery process and you will be under general anesthesia during the procedure.


It is one of the popular bone marrow transplant procedures. Here, the donor receives five shots from the surgeon. These are used to remove the stem cells from the marrows into the bloodstream. Then h/she collects blood through an IV line. RBC-containing stem cells are separated from the whole collection.

Then the surgeon starts the operation to you. H/she installs a central venous catheter into the upper right chest. Fluids containing the donor stem cells are transmitted into your heart through such opening.

Effective stem cells are dispersed through your blood cells into the spongy tissues. These cells gradually establish in their new position and start growing there. With time, these become integral to your physiological processes.

Surgeons repeat the process several times within a few days to ensure complete transmutation,


Your surgeon does not take the central venous catheter called port back. Besides transfused blood, you will get liquids and nutrients through this.

Your ability to fight the infections vide medications is also tested in the recovery process following the surgery process.

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