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Overview

The kidney is an essential organ in our body. The bean-shaped organs are placed on either side of the spine under the coverage of the lower ribcage. The organ works in filtering blood and removal of excess water, salt, and other abusive substances in the body. Most of these materials flow through renal tubules.

Kidney malignant growth happens when the cells in the kidney unusually start to develop. Kidneys are a couple of bean-shaped organs that are joined to the upper back mass of the stomach and are ensured by the lower rib limit. On the superior shaft of each kidney lies the adrenal organ. Both the adrenal & kidney organs are encircled by a fat, slender fibrotic layer called Serota's sash. Renal have numerous capacities that incorporate:

  • Filtration /detoxification of blood
  • Balancing of body fluids
  • Maintaining electrolyte levels
  • Removing nitrogenous waste from the body
  • Maintaining blood pressure by releasing the hormone renin
  • Releases erythropoietin which helps in the production of red blood cells

Even though renal malignancy is a moderately uncommon one, it is among the 10 most normal diseases in the two people. While the general lifetime hazard for creating renal malignancy in men is around 1 out of 46 (2.02%), it is around 1 in 82(1.02%) in ladies. Worldwide, around 338000 individuals are determined to have renal malignancy consistently. Because of the utilization of newer imaging strategies, the pace of renal malignancy cases has expanded since the 1900s however the passing rates have stayed stable for a long time.

In India, the occurrence of renal malignancy is around 2/100000 populace among guys and around 1/100000 populace among females. 30-40% of patients with kidney cell carcinoma passed on because of sickness alone while 20% of death rates are related to prostate and urinary bladder carcinomas. For each 100-malignant growth enduring populace, just 2-3 of them will have renal disease, of which 1 out of 3 of them will have progressed renal malignancy.

The uncanny division of the cells in this region causes tumor formation in the line of the renal compartment. Therefore, Kidney Cancer is also referred to as renal cancer.

The kidneys are a pair of bean-shaped organs. Each piece in the team is about the size of a fist. The set of organs are attached to the upper back wall of the abdomen. The lower rib cage protects the organ.

One of these organs stays to the left and the other to the right of the backbone. The upper and lower portions of each piece are medically referred to as the superior pole and the inferior pole.

Blood carries excess water, salt, and waste products to the abdomen portion. Our kidney converts the substances into urine and helps those pass through our body.

Urine collects in the center of each piece of kidney. The area where the urine is collected is called the renal pelvis.

The excreting materials then leave the kidney zone through long slender tubes called a ureter. It leads to the bladder, and the urine is stored there till you feel to urinate. The organ performs several other jobs too. These include:

Kidney Cancer Treatment in India
Kidney Cancer Treatment Cost in India
  • It helps control blood pressure by producing rennin, a stipulated hormone.
  • It ensures that our body has enough blood units. A hormone called erythropoietin is produced in the process.

Kidney Cancer Treatment Cost in India

  • One can easily find low-cost kidney cancer treatment in India as compared to other western countries.
  • Along with quality services and satisfaction for kidney cancer treatment at affordable prices, most international patients prefer India.
  • The kidney cancer treatment costs range from $5,000 to $10,000. It depends upon the complexity of the treatment and services facilities from the hospital.

Get details of the Kidney Cancer Treatment hospitals in India that offer higher success rates at affordable costs. The cost of Kidney Cancer Treatment varies widely. For Kidney Cancer Surgery, it is necessary to choose the proper specialist/oncologist in India. HMSDESK helps patients seeking medical care and specialty treatments from the Best Oncologist in India. Various hospitals and clinics in India have gained massive popularity all over the world. International patients preferred places for the surgery or treatment would be tier one, in developed cities like Bangalore, Chennai, Hyderabad, Kolkata, Mumbai, Delhi, Mangalore, Kochi, Jaipur, and Pune.

Causes

Kidney cancer begins when some of the units develop changes in their DNA. DNA contains the instructions about the things to do by a section. With change occurred in the DNA, cells get the instruction to grow and divide fast. It results in the formation of under-developed pieces. Accumulation of such abnormal variety helps form a tumor whose size can extend beyond the kidney. Some cells break off and spread to distant parts of the body.

Kidney Cancer Risks

A lot of factors increase the risks of having renal cancer. These include:

Age: Doctors agree with the fact that the chances of acquiring renal cancer increase with age.

Smoking: Physicians debar the practice of smoking for those whom they suspect to have the infection.

Hypertension: High blood pressure increases the probability of kidney disease.

Obesity: Obese people have a higher risk of kidney cancer.

Family History: The chance of having the disease increases if members of the family had the disease in the previous years.

Hereditary Effect; People have greater chances of renal cancer if they get some inherited syndromes. These syndromes include tuberous sclerosis complex or hereditary papillary renal cell carcinoma.

Kidney Cancer symptoms
Kidney Cancer stages

Kidney Cancer Symptoms

It is hard to make any identification of symptoms for renal cancer. With an increase in tumor size, the symptoms are likely to appear. The common signs include:

  • Pain the side of the body.
  • Blood in the urine. It may make the urine slightly rusty to deep red.
  • Weight loss for no apparent reason.
  • Loss of appetite.
  • Anaemia

Of those mentioned above, blood in the urine is known as the Basic Symptoms of the Disease. If your doctor knows about the prevalence of the factor, he will unhesitatingly denounce the presence of a tumor in the kidney.

Disease Types

Renal cell carcinoma

The disease is also known as renal cell cancer and is the most prevalent type. It usually grows as a single lump within a kidney. Sometimes there are two or more swelling in a single kidney. There could be tumors in both of the kidneys simultaneously.

There are several subtypes of the disease; these are mainly based on how the infected cells look in the lab. Doctors need to know the subtype to plan the treatment.

  • The clear cell renal carcinoma: It is the most common form of RCC. Almost 70% of the cases belong to this category.
  • The papillary renal cell carcinoma: It is the second most common subtype that forms little finger-like projections called papillae in most of the lumps. The disease is also called chromophilic as these appear to have certain dyes. It looks pink when viewed under a microscope.
  • Chromophobe renal cell carcinoma: It accounts for about 5% of the total cases. The cancers look pale too like the clear cells. These are much larger and have certain other features. It can be recognized when looked at from close.

Other types of Kidney Tumors

The disease can be of two types

  • The carcinoma types
  • Benign types.

Transitional Cell Carcinoma

The disease does not star in the kidney itself, but the lining of the renal pelvis. The lining is made up of transitional cells. These appear like the sections appear in the line of the ureter and bladder. The disease is often linked to cigarette smoking. Often it is exposed to certain cancer-causing chemicals in the workplace. The ailment bears similar signs and symptoms as that of RCC. These include blood in the urine, and sometimes, back pain too.

Wilms Tumor

The disease mainly occurs in children and sometimes in adults too. The condition is rare among adults. The tumor starts when the cells in the body begin to mutate. These cells in nearly any part of the body can become cancerous. The disease can also be spread to other areas of the body. The tumors are grouped into two major types:

Favorable Histology

The cancerous cells in these tumors do not look quite familiar. About 90 percent of the Wilms cases belong to this type. Chances of recovery are significantly high.

Anaplastic Histology

Look in these cancer cells is significantly different. The compartment nuclei tend to be very large and distorted.

Doctors find the deep-spread conditions harder to treat than those where the anaplasia is fixed to a specific part of the lumps.

The benign tumors

Kidney tumors belonging to the benign type are treated by removing and destroying them. The treatment types are similar to other cancer types, including surgery and radiofrequency ablation.

The doctors decide the treatment type based on some other factors. These include the size of the lump, the numbers and location of the tumors, and the person's overall health.

Angiomyolipoma

It is the most typical type of benign disease and is found often. The ailment develops sporadically or in people with tuberous sclerosis.

Tuberous sclerosis is a genetic condition that affects the heart, brain, eyes, brain, lungs, and skin. Angiomyolipoma comprises different types of connective tissues. If these do not cause any symptoms, these are often watched closely. Treatment is planned if it suddenly starts to cause problems.

Diagnosis

Kidney cancer signs and symptoms can be found with several diagnostic tests that help to confirm the presence of cancer. Procedures conducted for Diagnosis of Kidney Cancer Treatment include the following:

Blood and Urine Tests

Checking for any disorder in the blood flow may help the doctor find out the traces of cancer. Urine tests are also conducted to further confirming the signs and symptoms.

Biopsy

It involves removing a small sample of cells from the areas of suspect in the kidney. The model will be required to test under an intense microscope. It will help them to look for signs and symptoms of cancer. However, the process is always recommended.

Imaging Tests

Tests like CT scan, MRI, or USG allow the doctor to visualize the kidney tumor or other abnormality. The other imaging tests include:

  • Intravenous pyelogram.
  • Bone Scan.
  • Chest X-Ray.
  • Angiography.
  • Fine needle aspiration and needle core biopsy.
  • Positron emission tomography or PET.

Treatments

The Procedure for Kidney Cancer Treatment targets to remove cancer. Most of the renal cancers belong to the recurrent type. Doctors resort to the advanced level of treatment to heal the cases. It makes treatment costs in India a bit higher yet much lower than those offered in developed countries.

The following methods are practiced:

Surgery

If cancer can't be removed entirely at the time of operation, surgeons work to remove cancer to the possible extent. The surgical process may be used to remove cancer that has spread to another area of the body.

Targeted Therapy

Targeted drug treatments are popular these days. The treatments focus on specific abnormalities present in the cancer cells. After blocking such aberrations, the targeted drug treatments will lead cancer cells to death. Doctors may recommend testing the cancer cells to check which targeted drugs are going to be most effective.

Chemotherapy

Chemotherapy involves the use of chemicals to kill cancer cells. The use of medication may also be required, along with chemotherapy under certain circumstances. Depending on the patient's condition, the chemotherapy process may also be applied along with other techniques of cancer treatment.

Chemotherapy cost in India differs a lot depending on the overall physical condition of the patient and the level of cancer penetration.

Immunotherapy

The treatment method uses the patient's immune system to fight the malignancy. A substance made in the body or made in a lab is used to boost, direct, and restore the natural potential against the disease. The treatment types belong to the following class:

The immune checkpoint inhibitor therapy

Numerous immune cells like the T cells and some other cancer enigmas have specific proteins. These are called checkpoint proteins.

When the malignant cells have more massive amounts of these proteins, they will not be attacked and killed by T cells.

The immune checkpoint inhibitors block these proteins, thereby increasing the ability to kill cancerous blocks. These are used to treat patients with advanced renal cell cancer. Surgery cannot remove such tumors.

After Procedure

Advanced and recurrent kidney cancer-sometimes even after surgery cancer recurs or some advanced kidney cancers cannot be removed altogether in one surgical operation. So few of the procedures done after the main surgical treatment consists of:

  • Surgery is done to eliminate as much cancer as could be expected from the kidney and different organs if the disease got spread
  • Targeted drug treatment helps in blocking the abnormalities causing the cancer cells to die
  • Immunotherapy uses the immune system of the body to fight the cancer cells by interfering with the protein which blocks the body’s immune system to identify them
  • Radiotherapy uses high powered energy beams to control cancer in the kidney and spread to other organs
  • Clinical trials

Integrated Therapy: Used to support the side effects of the after-treatment which include

1. Art treatment

2. Exercise

3. Massage therapy

4. Music treatment

5. Relaxation workouts

6. Meditation

7. Spirituality

kidney cancer types
kidney cancer causes

Recovery from Kidney Cancer

1. When compared to an open procedure, a laparoscopic procedure always leads to quick and easier recovery.

2. Deal with yourself during treatment. Eat healthy food full of leafy foods and fruits, be truly dynamic when you feel like it, and get enough rest so you wake to feel rested every day.

3. Accumulate an encouraging group of people from loved ones that helps to focus on your recovery.

4. Get mental health counseling if needed. Talk with your primary care physician or another person from your medical care group about getting a reference to psychological well-being proficient, for example, a confirmed social worker, clinician, or specialist.

5. Follow up care and regular doctor visits

6. Maintaining a healthy weight by eating a healthy diet

7. Keep physically active and avoid alcohol and smoking.

Risk After Treatment

  • Recurrence of kidney cancer
  • Delayed healing of the wound
  • Secondary infection of the injury
  • Second cancers after treatment like bladder cancer, prostate cancer, ureter cancer, etc.
  • Depression or anxiety
  • Loss of appetite
  • Bloating and inflammation
  • Constipation
  • Loss of hair (alopecia)
  • Sores in the mouth and lips
  • Dizziness and vomiting
  • The scarring
  • Shortness of respiration (dyspnea)
  • Irritation in the skin
  • Problems with sleep (insomnia)
  • Fatigue

Frequently Asked Questions about Kidney Cancer Treatment

What is metastatic renal cell carcinoma?

It means that cancer has spread beyond the level of the kidney.

Does renal tumor spread fast?

The spread of malignancy depends on the type. Grade I type look like normal kidney cells. These tend to grow faster too. It is better to ask the doctor about the malignancy type.

What are the treatment options for renal cancer?

These include surgery, immunotherapy, chemotherapy, and targeted therapy.

What is Hippel-Lindau syndrome?

It is a rare hereditary syndrome. Its characteristics include the growth of tumors and fluid-filled sacs.

What are the types of renal cell carcinoma?

These include Clear cell, Papillary, Collecting duct, and Chromophobe.

Should everyone with kidney cancer get a second opinion?

Patients should get a second opinion about the healthcare providers before deciding on the treatment. The reasons may be:

  • The case is a rare type of cancer.
  • The person owns health insurance.
  • The patient is not comfortable with the treatment offered.

What is metastatic renal cell carcinoma?

It means that cancer has spread beyond the level of the kidney.

What are the treatment options for renal cancer?

These include surgery, immunotherapy, chemotherapy, and targeted therapy.

What is Hippel-Lindau syndrome?

It is a rare hereditary syndrome. Its characteristics include the growth of tumors and fluid-filled sacs.

What are the types of renal cell carcinoma?

These include Clear cell, Papillary, Collecting duct, and Chromophobe.

Should everyone with kidney cancer get a second opinion?

Patients should get a second opinion about the healthcare providers before deciding the treatment. The reasons may be:

  • The case is a rare type of cancer.
  • The person owns health insurance.
  • The patient is not comfortable with the treatment offered.

For Surgery Some Countries From Which Patients Travel To India:

Best Cancer Hospitals in India

Hospitals in India offer State-of-the-art equipment and the latest technologies.

  • Fortis Hospital
  • Blk Super Speciality Hospital
  • Sir Ganga Ram Hospital
  • Saifee Hospital
  • Jaslok Hospital
  • Global Hospital
  • Medanta Medicity Hospital
  • HCG Hospital
  • Action Cancer Hospital
  • SIMS Hospital, Chennai
  • MIOT Hospital, Chennai
  • Max Super Speciality Hospital
  • Bgs Gleneagles Global Hospital
  • Nanavati Super Speciality Hospital
  • Manipal Hospital
  • Apollo Hospital
  • S L Raheja Fortis Hospital
  • Asian Heart Hospital
  • Hiranandani Hospital
  • Apollo Hospitals
  • BLK Super Speciality Hospital
  • Yashoda Cancer Institute, Hyderabad
  • Saifee hospital, Mumbai
  • Bombay Hospital & Medical Research Centre

Top Cancer Specialist in India

  • Dr. Sanghavi Meghal Jayant
  • Dr. Mathangi
  • Dr. Raja Sundaram
  • Dr. Jagdeesh Kulkarni
  • Dr. Rahul Bhargava
  • Dr. Manas Kalra
  • Dr. C Rayappa
  • Dr. P Jagannath
  • Dr. Adwani
  • Dr. Vikas Dua
  • Dr. Jalaj Baxi
  • Dr. Rajeev Agarwal
  • Dr. Ashok Vaid
  • Dr. Narmada Prasad
  • Dr. Arun Prasad
  • Dr. Deepak Sari
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